Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL7098297 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7101408 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7095713 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7094790 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7095271 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7095703 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7096301 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| Monoethanolamine SCHEMBL7098553 | 1.00 | SMPD1 (0.34) | SMPD1FDPSRRM1GPR84FFAR1 | |
| SCHEMBL930252 | 0.91 | GPR84 (0.38) | GPR84FFAR1HSPD1BLMHSPE1 | |
| SCHEMBL9645076 | 0.91 | GPR84 (0.38) | GPR84FFAR1HSPD1BLMHSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964036-B1 | Water-based ball-point pen ink composition | PILOT INK CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0964036-A2 | Water-based ball-point pen ink composition | THE PILOT INK CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |