Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.58 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15810270 | 0.95 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL31488325 | 0.94 | CCR2 (0.63) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL14857318 | 0.90 | CCR2 (0.55) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL25590758 | 0.90 | CCR2 (0.55) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL10916213 | 0.90 | CCR2 (0.57) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL25590935 | 0.89 | CCR2 (0.57) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL25590754 | 0.89 | CCR2 (0.57) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL3434642 | 0.83 | CCR2 (0.47) | CCR2CCR1CCR5CXCR4 | |
| SCHEMBL4006271 | 0.83 | CCR2 (0.54) | CCR2CCR1CCR5CXCR4HTT | |
| SCHEMBL8365578 | 0.83 | HTT (0.58) | CCR2CCR1CCR5CXCR4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0128775-B1 | RESINOUS COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4612346-A | BLEND OF POLYAMIDE AND MODIFIED POLYOLEFIN | TORAY INDUSTRIES, INC. (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0175309-A2 | A method for producing l-lysine | TORAY INDUSTRIES, INC. (JP) | 1986-03-26 | — | — | EP | disclosed |
| EP-0128775-A2 | Resinous composition | TORAY INDUSTRIES, INC. (JP) | 1984-12-19 | — | — | EP | disclosed |