Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27511408 | 0.98 | MTNR1A (0.53) | MTNR1AMTNR1BF2PLGPLAU | |
| SCHEMBL7013647 | 0.87 | MTNR1A (0.50) | MTNR1AMTNR1BF2PLGPLAU | |
| SCHEMBL7011527 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1BF2PLGPLAU | |
| SCHEMBL7238438 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL7011236 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL7094962 | 0.79 | MAPT (0.56) | MTNR1AMTNR1BF2PLGPLAU | |
| SCHEMBL7094406 | 0.78 | MTNR1A (0.55) | MTNR1AMTNR1BF2PLGPLAU | |
| SCHEMBL27514052 | 0.78 | MTNR1A (0.50) | MTNR1AMTNR1BF2PLGPLAU | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.78 | MAPT (0.55) | MTNR1AMTNR1BF2PLGPLAU | |
| SCHEMBL7228935 | 0.75 | MTNR1A (0.56) | MTNR1AMTNR1BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |