Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 11/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099599 | 1.00 | ITGA4 (0.47) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7103726 | 0.90 | ITGB1 (0.49) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7103727 | 0.90 | ITGB1 (0.49) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7103678 | 0.89 | MEN1 (0.46) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7103675 | 0.89 | MEN1 (0.46) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7102696 | 0.88 | ITGA4 (0.47) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7102700 | 0.88 | ITGA4 (0.47) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7098697 | 0.88 | NPSR1 (0.52) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7098693 | 0.88 | NPSR1 (0.52) | ITGA4ITGB1NPSR1MEN1KMT2A | |
| SCHEMBL7105774 | 0.87 | NPSR1 (0.46) | ITGA4ITGB1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |