Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050308 | 0.77 | TSHR (0.55) | TSHRNPSR1ACHEPARP1METAP1 | |
| SCHEMBL8966129 | 0.76 | TSHR (0.62) | TSHRNPSR1DYRK1AACHEPARP1 | |
| SCHEMBL4552573 | 0.76 | TSHR (0.54) | TSHRNPSR1ACHEPARP1METAP1 | |
| SCHEMBL7097158 | 0.73 | RNASEH1 (0.34) | GAA | |
| SCHEMBL5037320 | 0.70 | TSHR (0.57) | TSHRNPSR1DYRK1AACHEPARP1 | |
| SCHEMBL3921668 | 0.70 | TSHR (0.57) | TSHRNPSR1DYRK1AACHEPARP1 | |
| SCHEMBL3926777 | 0.70 | TSHR (0.57) | TSHRNPSR1DYRK1AACHEPARP1 | |
| SCHEMBL7099999 | 0.70 | TSHR (0.57) | TSHRNPSR1DYRK1AACHEPARP1 | |
| SCHEMBL3921663 | 0.70 | TSHR (0.57) | TSHRNPSR1DYRK1AACHEPARP1 | |
| SCHEMBL3926780 | 0.70 | TSHR (0.57) | TSHRNPSR1DYRK1AACHEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140952-B1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | BIOAGENCY AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1140952-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | Jomaa Pharmaka GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037477-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | JOMAA PHARMAKA GMBH (DE) | 2000-06-29 | — | — | WO | disclosed |