SCHEMBL7100055

SCHEMBL7100055

O=C(O)c1ccc2c(c1C(=O)O)S(=O)(=O)NC2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 14/20 0.41
CA9 Q16790 14/20 0.41
CA2 P00918 12/20 0.41
CA7 P43166 7/20 0.41
CA1 P00915 5/20 0.41
CA4 P22748 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
BCHE P06276 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
KMT2A Q03164 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
GLO1 Q04760 1/20 0.36
XDH P47989 1/20 0.33
CHEK1 O14757 1/20 0.33
DAPK3 O43293 1/20 0.33
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12474969 0.82 CA12 (0.46) CA12CA9CA2CA7CA1
SCHEMBL1081860 0.78 CA12 (0.50) CA12CA9CA2CA7CA1
SCHEMBL8159236 0.75 CA12 (0.34) CA12CA9CA2CA7CA1
SCHEMBL9442809 0.72 CA12 (0.40) CA12CA9CA2CA7CA1
Phthalic Acid SCHEMBL27956797 0.68 CA12 (0.76) CA12CA9CA2CA7CA1
Phthalic Acid SCHEMBL27835684 0.68 CA12 (0.76) CA12CA9CA2CA7CA1
SCHEMBL6846764 0.67 CYP1A2 (0.50) CA12CA9CA2CA7CA1
SCHEMBL6671225 0.67 PARP1 (0.42) KDM4ELMNAKMT2ACHEK1DYRK1A
SCHEMBL30504559 0.67 PARP1 (0.42) KDM4ELMNAKMT2ACHEK1DYRK1A
SCHEMBL10656700 0.67 CA12 (0.49) CA12CA9CA2CA7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427349-B1 Method for the preparation of polydicarboxysaccharides TNO (NL) 1995-07-12 EP claimed
EP-0427349-A2 Method for the preparation of polydicarboxysaccharides NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1991-05-15 EP claimed
JP-4175301-A None JP disclosed
EP-0946598-B1 SUPERABSORBENT MATERIAL AND METHOD FOR PRODUCING SAID MATERIAL SCA HYGIENE PROD ZEIST BV (NL) 2003-08-06 EP disclosed
US-20030051726-A1 Process for the oxidation of starch DEGUSSA AG (DE) 2003-03-20 US disclosed
CN-1100794-C Thermoplastic biodegradable polysaccharide derivatives, process for the manufacture thereof and use thereof WOLFF WALSRODE AG (DE) 2003-02-05 CN disclosed
US-6331619-B1 BIODEGRADATION SCA HYGIENE PRODUCTS ZEIST B.V. (NL) 2001-12-18 US disclosed
EP-0946598-A1 SUPERABSORBENT MATERIAL AND METHOD FOR PRODUCING SAID MATERIAL SCA Hygiene Products Zeist B.V. (NL) 1999-10-06 EP disclosed
WO-1999015256-A1 PROCESS OF CLEANING FILTERS NORIT MEMBRAAN TECHNOLOGIE B.V. (NL) 1999-04-01 WO disclosed
EP-0526494-B1 METHOD FOR PREPARATION OF A CALCIUM-BINDING POLYDICARBOXY-INULIN AND ITS USE AS REPLACEMENT FOR PHOSPHATES IN DETERGENTS TNO (NL) 1998-12-09 EP disclosed
WO-1998027117-A1 SUPERABSORBENT MATERIAL AND METHOD FOR PRODUCING SAID MATERIAL SCA HYGIENE PRODUCTS ZEIST B.V. (NL) 1998-06-25 WO disclosed
EP-0427349-B1 Method for the preparation of polydicarboxysaccharides TNO (NL) 1995-07-12 EP disclosed
EP-0427349-B1 Method for the preparation of polydicarboxysaccharides TNO (NL) 1995-07-12 EP disclosed
US-5326864-A Method for the preparation of calcium-binding polycarboxy compounds based on polysaccharides, and replacements for phosphates in detergents, based on these polycarboxy compounds NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1994-07-05 US disclosed
EP-0526494-A1 METHOD FOR PREPARATION OF CALCIUM-BINDING POLYCARBOXY COMPOUNDS BASED ON POLYSACCHARIDES, AND REPLACEMENTS FOR PHOSPHATES IN DETERGENTS, BASED ON THESE POLYCARBOXY COMPOUNDS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1993-02-10 EP disclosed
JP-H04175301-A PREPARATION OF POLYDICARBOXYSACCHARIDES AND SUBSTITUTE OF PHOSPHATE IN DETERGENT BASED ON POLYDICARBOXYSACCHARIDES NEDERLAND CENTR ORG TOEGEPAST NATUUR ONDER 1992-06-23 JP disclosed
WO-1991017189-A1 METHOD FOR PREPARATION OF CALCIUM-BINDING POLYCARBOXY COMPOUNDS BASED ON POLYSACCHARIDES, AND REPLACEMENTS FOR PHOSPHATES IN DETERGENTS, BASED ON THESE POLYCARBOXY COMPOUNDS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1991-11-14 WO disclosed
EP-0427349-A2 Method for the preparation of polydicarboxysaccharides NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1991-05-15 EP disclosed
EP-0427349-A2 Method for the preparation of polydicarboxysaccharides NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1991-05-15 EP disclosed
EP-0427349-A2 Method for the preparation of polydicarboxysaccharides NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1991-05-15 EP disclosed