Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081860 | 0.85 | CA12 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL5093607 | 0.80 | CA12 (0.45) | CA12CA9CA2CA1CA7 | |
| SCHEMBL19586659 | 0.79 | CA12 (0.43) | CA12CA9CA2CA1CA7 | |
| SCHEMBL8995896 | 0.78 | CA12 (0.44) | CA12CA9CA2CA1CA7 | |
| SCHEMBL7763714 | 0.78 | CA12 (0.44) | CA12CA9CA2CA1CA7 | |
| SCHEMBL6739070 | 0.76 | CA12 (0.41) | CA12CA9CA2CA1CA7 | |
| SCHEMBL7597306 | 0.75 | CA12 (0.36) | CA12CA9CA2CA1CA7 | |
| SCHEMBL193750 | 0.75 | CA12 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL230481 | 0.75 | CA9 (0.50) | CA12CA9CA2CA1CA7 | |
| SCHEMBL7287038 | 0.73 | RET (0.56) | CA12CA9CA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |