SCHEMBL7100075

SCHEMBL7100075

CC(=O)OC(C)(N)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2C19 P33261 3/20 0.47
HIF1A Q16665 1/20 0.47
KCNN4 O15554 2/20 0.42
ALDH1A1 P00352 3/20 0.42
ALOX15 P16050 1/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1751011 0.89 CYP2C9 (0.46) CYP1A2CYP2D6MAPTKMT2AKIF11
SCHEMBL2944462 0.86 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL2944463 0.86 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL27312692 0.82 CYP1A2 (0.43) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL11379208 0.81 CYP2C19 (0.52) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL28117943 0.81 TDP1 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL8592497 0.80 CYP1A2 (0.53) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL28757843 0.79 CYP2C19 (0.47) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL42458 0.79 ALDH1A1 (0.56) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL8324538 0.78 CYP2C19 (0.48) CYP1A2CYP2D6MAPTKMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106957315-B N- replaces benzenesulfonyl-azaindole oxybenzamide class compound and its prepares the purposes of drug 中国人民解放军第二军医大学 2019-08-13 CN disclosed
CN-105555877-B Colorants grafted with 6 '-deoxy-6' - (piperazinyl) lactose moieties 佛罗伦萨大学 2017-04-05 CN disclosed
CN-100441556-C Triphenylalkene derivatives and their use as selective estrogen receptor modulators HORMOS MEDICAL LTD (FI) 2008-12-10 CN disclosed
CN-1861555-A Triphenylalkene derivatives and their use as selective estrogen receptor modulators HORMOS MEDICAL LTD (FI) 2006-11-15 CN disclosed
CN-1263720-C Triphenylalkene derivatives and their use as selective estrogen receptor modulators HORMOS MEDICAL OY LTD (FI) 2006-07-12 CN disclosed
CN-1245381-C Phenylglycine derivatives HOFFMANN LA ROCHE (CH) 2006-03-15 CN disclosed
EP-1326864-A2 ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS PFIZER PHARMACEUTICALS INC. (JP) 2003-07-16 EP disclosed
EP-1326606-A2 EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS PFIZER PHARMACEUTICALS INC. (JP) 2003-07-16 EP disclosed
CN-1399622-A Triphenylalkene derivatives and their use as selective estrogen receptor modulators HORMOS MEDICAL OY LTD (FI) 2003-02-26 CN disclosed
WO-2002032422-A2 EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS PFIZER PHARMACEUTICALS INC. (JP) 2002-04-25 WO disclosed
WO-2002032900-A2 ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS PFIZER PHARMACEUTICALS INC. (JP) 2002-04-25 WO disclosed
CN-1334798-A Phenylglycine derivatives HOFFMANN LA ROCHE (CH) 2002-02-06 CN disclosed