Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 14/20 | 0.60 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | MTAP | Q13126 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506019 | 1.00 | PNP (0.60) | PNPHPRT1MTAP | |
| SCHEMBL5606739 | 1.00 | PNP (0.60) | PNPHPRT1MTAP | |
| Hydrochloric Acid SCHEMBL4065724 | 0.99 | PNP (0.59) | PNPHPRT1MTAP | |
| SCHEMBL505709 | 0.87 | PNP (0.64) | PNPHPRT1MTAP | |
| SCHEMBL14156772 | 0.87 | PNP (0.58) | PNPMTAP | |
| SCHEMBL8246938 | 0.87 | PNP (0.64) | PNPHPRT1MTAP | |
| SCHEMBL5606527 | 0.87 | PNP (0.64) | PNPHPRT1MTAP | |
| Hydrochloric Acid SCHEMBL4830734 | 0.86 | PNP (0.63) | PNPHPRT1MTAP | |
| SCHEMBL4840335 | 0.83 | HPRT1 (0.48) | PNPHPRT1MTAP | |
| Forodesine SCHEMBL506383 | 0.82 | PNP (0.75) | PNPMTAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165564-A4 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | IND RES LTD (NZ) | 2003-01-22 | — | — | EP | claimed |
| EP-1165564-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2002-01-02 | — | — | EP | claimed |
| WO-2000061783-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2000-10-19 | — | — | WO | claimed |