Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100238 | 0.87 | PNP (0.60) | PNPMTAP | |
| SCHEMBL506019 | 0.87 | PNP (0.60) | PNPMTAP | |
| SCHEMBL5606739 | 0.87 | PNP (0.60) | PNPMTAP | |
| Hydrochloric Acid SCHEMBL4065724 | 0.86 | PNP (0.59) | PNPMTAP | |
| SCHEMBL8246938 | 0.85 | PNP (0.64) | PNPMTAP | |
| SCHEMBL505709 | 0.85 | PNP (0.64) | PNPMTAP | |
| SCHEMBL5606527 | 0.85 | PNP (0.64) | PNPMTAP | |
| Hydrochloric Acid SCHEMBL4830734 | 0.84 | PNP (0.63) | PNPMTAP | |
| Forodesine SCHEMBL8407141 | 0.80 | PNP (0.75) | PNPMTAP | |
| Forodesine SCHEMBL15740230 | 0.80 | PNP (0.75) | PNPMTAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390890-B2 | Inhibitors of nucleoside metabolism | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2008-06-24 | — | — | US | disclosed |
| US-20070197561-A1 | Inhibitors of nucleoside metabolism | BIOCRYST PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197561-A1 | Inhibitors of nucleoside metabolism | CFH, CBR3, SLCO2B1 | PNP 35/4885MTAP 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.