Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952425 | 0.96 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10457292 | 0.93 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL3854884 | 0.92 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL27797310 | 0.91 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL11600896 | 0.91 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| 1,4-Butanediol SCHEMBL9333775 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7959080 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL5936316 | 0.90 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1514927 | 0.90 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Styrene SCHEMBL11878203 | 0.88 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893456-B1 | Process for producing modified acrylic rubber | NIPPON MEKTRON KK (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6380318-B1 | PEROXIDE CURABLE; SOLVENT-FREE | NIPPON MEKTRON, LIMITED (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-0893456-A1 | Process for producing modified acrylic rubber | Nippon Mektron, Limited (JP) | 1999-01-27 | — | — | EP | disclosed |