Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457292 | 0.97 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL7100314 | 0.96 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL3854884 | 0.95 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| 1,4-Butanediol SCHEMBL9333775 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7959080 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL313059 | 0.91 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7997856 | 0.91 | TSHR (0.66) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL8161487 | 0.90 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9770236 | 0.90 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL3900902 | 0.90 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4306201-A | — | — | None | — | — | JP | disclosed |
| US-8466214-B2 | Core-shell impact modifiers for transparent polymer matrices | ARKEMA FRANCE (FR) | 2013-06-18 | — | — | US | disclosed |
| CN-101878270-B | Impact resistant, flame retardant thermoplastic molding composition | BAYER MATERIALSCIENCE LLC | 2013-01-09 | — | — | CN | disclosed |
| US-20110136980-A1 | NOVEL CORE-SHELL IMPACT MODIFIERS FOR TRANSPARENT POLYMER MATRICES | ARKEMA FRANCE (FR) | 2011-06-09 | — | — | US | disclosed |
| JP-H04306201-A | METHOD FOR RADICAL POLYMERIZATION | TOAGOSEI CHEM IND CO LTD | 1992-10-29 | — | — | JP | disclosed |
| US-4879348-A | IMPACT MODIFICATION OF THERMOPLASTIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-11-07 | — | — | US | disclosed |