Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395990 | 0.86 | GSK3B (0.61) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7100354 | 0.81 | GSK3B (0.41) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7852234 | 0.81 | GSK3B (0.51) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4972151 | 0.80 | GSK3B (0.46) | GSK3BALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7022779 | 0.77 | GSK3B (0.73) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4970607 | 0.76 | GSK3B (0.55) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4970968 | 0.75 | GSK3B (0.57) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7854664 | 0.73 | GSK3B (0.51) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4400415 | 0.73 | GSK3B (0.63) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7852598 | 0.73 | GSK3B (0.49) | GSK3BALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |
| EP-1087963-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | Chiron Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |