Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 1.00 |
| ▸ | ITGAV | P06756 | 20/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.58 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103664 | 0.79 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL7099691 | 0.79 | ITGB3 (0.67) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL7105700 | 0.77 | ITGB3 (0.94) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL7103918 | 0.71 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7105309 | 0.71 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL7099298 | 0.70 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL2841463 | 0.70 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL2836649 | 0.70 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL2833061 | 0.70 | ITGB3 (0.54) | ITGB3ITGAV | |
| SCHEMBL7105114 | 0.70 | NPC1 (0.63) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649613-B1 | Integrin inhibitors | MERCK PATENT GMBH (DE) | 2003-11-18 | — | — | US | disclosed |
| EP-1194401-B1 | DIACYLHYDRAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |