Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12005283 | 0.70 | PIK3CG (0.33) | PIK3CG | |
| SCHEMBL3292267 | 0.67 | PIK3CG (0.47) | PIK3CG | |
| SCHEMBL1378685 | 0.65 | PIK3CG (0.46) | PIK3CG | |
| SCHEMBL30124132 | 0.61 | EGFR (0.54) | PIK3CG | |
| SCHEMBL35632 | 0.61 | EGFR (0.54) | PIK3CG | |
| SCHEMBL3536096 | 0.59 | PIK3CG (0.67) | PIK3CG | |
| SCHEMBL30290978 | 0.58 | PIK3CG (0.41) | PIK3CG | |
| SCHEMBL30611771 | 0.58 | PIK3CG (0.41) | PIK3CG | |
| SCHEMBL2490862 | 0.58 | PIK3CG (0.41) | PIK3CG | |
| SCHEMBL2049528 | 0.58 | EGFR (0.45) | PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357114-A1 | Substituted pyrimidin-2,4(1H,3H)-diones as inhibitors of Matrix Metalloproteinases (MMP) | IBFB GmbH Privates Institut für biomedizinische Forschung und Beratung (DE) | 2003-10-29 | — | — | EP | disclosed |