SCHEMBL7100535

SCHEMBL7100535

CCCN(CCC)c1ccc(N)c(C)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.72
SKP2 Q13309 1/20 0.46
TDP1 Q9NUW8 5/20 0.43
ALDH1A1 P00352 5/20 0.43
CYP3A4 P08684 4/20 0.43
TSHR P16473 2/20 0.43
S1PR1 P21453 2/20 0.41
IGLV6-57 P01721 1/20 0.41
ESR1 P03372 2/20 0.40
AR P10275 2/20 0.39
ESR2 Q92731 1/20 0.39
CRHR1 P34998 1/20 0.38
GAA P10253 2/20 0.37
RAD52 P43351 1/20 0.37
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
RECQL P46063 2/20 0.36
PSMD14 O00487 1/20 0.36
GFER P55789 1/20 0.36
APAF1 O14727 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24720187 0.93 S100B (0.64) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL10798968 0.93 S100B (0.79) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL8590922 0.92 S100B (0.62) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL5499309 0.89 S100B (0.58) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL5499311 0.87 S100B (0.57) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL15244176 0.86 S100B (0.64) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL13422458 0.86 S100B (0.64) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL19980899 0.86 S100B (0.64) S100BSKP2TDP1ALDH1A1CYP3A4
SCHEMBL2890283 0.85 S100B (0.54) S100BSKP2ALDH1A1S1PR1IGLV6-57
SCHEMBL33702 0.85 S100B (0.85) S100BSKP2TDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869222-A CONTAINING AN ALWAYS PRESENT SOLID DEVELOPING AGENT HAVING SPECIFIED SOLUBILITY EASTMAN KODAK COMPANY (US) 1999-02-09 US claimed
US-8440663-B2 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrimidines as JAK-2 modulators and methods of use EXELIXIS, INC. (US) 2013-05-14 US disclosed
EP-0795785-B1 Photographic processing solutions EASTMAN KODAK CO (US) 2003-09-03 EP disclosed
US-6541191-B2 Mixture of antioxidant, black and white developer antifogging agents and pH buffer EASTMAN KODAK COMPANY 2003-04-01 US disclosed
US-20010041312-A1 Photographic processing solutions TWIST PETER JEFFERY (GB) 2001-11-15 US disclosed
US-5869222-A CONTAINING AN ALWAYS PRESENT SOLID DEVELOPING AGENT HAVING SPECIFIED SOLUBILITY EASTMAN KODAK COMPANY (US) 1999-02-09 US disclosed
EP-0795785-A1 Photographic processing solutions EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed