Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 9/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099850 | 1.00 | NAAA (0.47) | NAAAFAAHROCK2ROCK1 | |
| SCHEMBL13181403 | 0.75 | MEN1 (0.46) | NAAAFAAHROCK2ROCK1 | |
| SCHEMBL27453629 | 0.75 | ABL1 (0.38) | NAAAROCK2ROCK1 | |
| SCHEMBL6666419 | 0.74 | HSD17B3 (0.53) | — | |
| SCHEMBL13085731 | 0.73 | HSD17B3 (0.62) | — | |
| SCHEMBL17192796 | 0.73 | HSD17B3 (0.51) | — | |
| SCHEMBL27663680 | 0.72 | NPC1 (0.53) | — | |
| SCHEMBL27566212 | 0.72 | HSD17B3 (0.51) | — | |
| SCHEMBL7987176 | 0.71 | HDAC3 (0.50) | NAAAFAAH | |
| SCHEMBL9748000 | 0.71 | HSD17B3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |