SCHEMBL7101115

SCHEMBL7101115

C=CC(=O)NC(C)(C)NC(=O)C=C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TSHR P16473 4/20 0.44
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TGM2 P21980 7/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
LMNA P02545 2/20 0.33
FGFR4 P22455 1/20 0.32
GAA P10253 1/20 0.32
F13A1 P00488 1/20 0.31
TGM1 P22735 1/20 0.31
TGM3 Q08188 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3405723 0.87 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL26705 0.83
Formic Acid SCHEMBL28431084 0.82 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL2943903 0.81
Hydrochloric Acid SCHEMBL29176180 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL19457855 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Ammonia Solution, Strong SCHEMBL1036558 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL3468962 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Fluoride SCHEMBL21409814 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL35506 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114689847-A Novel lateral flow chromatography test strip based on molecular imprinting, preparation method and application of novel lateral flow chromatography test strip in detection of small molecular substance thiodiglycol 西南大学 2022-07-01 CN claimed
CN-111961153-B Thiodiglycol molecularly imprinted polymer and preparation method and application thereof 西南大学 2022-03-18 CN claimed
CN-111961153-A Thiodiglycol molecularly imprinted polymer and preparation method and application thereof 西南大学 2020-11-20 CN claimed
JP-56050927-A None JP disclosed
JP-56030970-A None JP disclosed
CN-114689847-A Novel lateral flow chromatography test strip based on molecular imprinting, preparation method and application of novel lateral flow chromatography test strip in detection of small molecular substance thiodiglycol 西南大学 2022-07-01 CN disclosed
CN-111961153-B Thiodiglycol molecularly imprinted polymer and preparation method and application thereof 西南大学 2022-03-18 CN disclosed
CN-111961153-A Thiodiglycol molecularly imprinted polymer and preparation method and application thereof 西南大学 2020-11-20 CN disclosed
EP-0846678-B1 Process for the preparation of N-hydrocarbyl-substituted amides LUBRIZOL CORP (US) 2003-09-10 EP disclosed
EP-0847988-B1 Process for the preparation of N-hydrocarbyl-substituted amides LUBRIZOL CORP (US) 2003-09-03 EP disclosed
US-5811580-A TREATING A NITRILE WITH AN ALKYLATING AGENT IN THE PRESENCE OF AN ACIDIFIED CLAY YIELDS ALKYL AMIDES THE LUBRIZOL CORPORATION (US) 1998-09-22 US disclosed
EP-0847988-A1 Process for the preparation of N-hydrocarbyl-substituted amides The Lubrizol Corporation (US) 1998-06-17 EP disclosed
EP-0846678-A1 Process for the preparation of N-hydrocarbyl-substituted amides The Lubrizol Corporation (US) 1998-06-10 EP disclosed
JP-S5650927-A MANUFACTURE OF SULFUR-CONTAINING COPOLYMER YAMAGATA DAIGAKU 1981-05-08 JP disclosed
JP-S5630970-A PYRILIUM DERIVATIVE AND SATURABLE ABSORBENT CONTAINING THE SAME NIPPON KANKO SHIKISO KENKYUSHO:KK 1981-03-28 JP disclosed
US-4013787-A CATIONIC POLYMERS SOCIETE ANONYME DITE: L'OREAL (FR) 1977-03-22 US disclosed