Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.65 |
| ▸ | UGCG | Q16739 | 2/20 | 0.64 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.61 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790480 | 1.00 | ASAH1 (0.65) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL7099901 | 1.00 | ASAH1 (0.65) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL7770736 | 0.86 | ASAH1 (0.73) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL8341808 | 0.85 | ALDH1A1 (0.71) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL7773484 | 0.85 | ALDH1A1 (0.71) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL7773486 | 0.85 | ALDH1A1 (0.71) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL13930311 | 0.79 | ASAH1 (1.00) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL360960 | 0.79 | ASAH1 (1.00) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL4239949 | 0.79 | ASAH1 (1.00) | ASAH1ALDH1A1ACER2UGCGSMPD2 | |
| SCHEMBL8340882 | 0.79 | ASAH1 (1.00) | ASAH1ALDH1A1ACER2UGCGSMPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782992-B1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6335444-B1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-01 | — | — | US | disclosed |
| US-5907039-A | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0782992-A1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) | 1997-07-09 | — | — | EP | disclosed |