Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.63 |
| ▸ | CA2 | P00918 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | CA9 | Q16790 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16317121 | 1.00 | CA12 (0.63) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL711079 | 0.88 | KDM4E (0.61) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL145541 | 0.88 | KDM4E (0.61) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL1270639 | 0.88 | KDM4E (0.61) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL9437414 | 0.88 | KDM4E (0.61) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL29365933 | 0.88 | KDM4E (0.61) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL25650142 | 0.88 | KDM4E (0.61) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL16875822 | 0.86 | CA12 (0.59) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL30511970 | 0.86 | CA12 (0.59) | CA12CA2KDM4ECA9RAB9A | |
| SCHEMBL13186635 | 0.86 | CA12 (0.59) | CA12CA2KDM4ECA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988330-B1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS | SUMITOMO BAKELITE CO (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6197984-B1 | Method for the preparation of copolymers of ethylene/norbornene-type monomers with nickel catalysts | THE B. F. GOODRICH COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0988330-A1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS | THE B.F. GOODRICH COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| US-5929181-A | Method for preparation of copolymers of ethylene/norbornene-type monomers with nickel catalysts | THE B.F.GOODRICH CO. (US) | 1999-07-27 | — | — | US | disclosed |
| WO-1998056837-A1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS | THE B.F. GOODRICH COMPANY (US) | 1998-12-17 | — | — | WO | disclosed |