Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 9/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30253496 | 1.00 | P2RX4 (0.36) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| Iodide SCHEMBL27879086 | 1.00 | P2RX4 (0.36) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| Iodide SCHEMBL27895829 | 0.98 | MAPT (0.36) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL1198914 | 0.98 | P2RX4 (0.37) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL29434173 | 0.98 | P2RX4 (0.37) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL29035745 | 0.96 | MEN1 (0.37) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL28221845 | 0.90 | P2RX4 (0.33) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL27890223 | 0.90 | P2RX4 (0.33) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL27536059 | 0.88 | HTR1A (0.33) | P2RX4HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL27542958 | 0.88 | HTR1A (0.33) | P2RX4HTR1ADRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288897-B | Application of neobynine derivatives in preparation of drugs for treating gastric cancer | 兰州大学 | 2022-05-27 | — | — | CN | claimed |
| CN-113321673-A | Preparation method and application of neobynine boric acid compound | 兰州大学 | 2021-08-31 | — | — | CN | claimed |
| CN-113288897-A | Application of neobynine derivatives in preparation of drugs for treating gastric cancer | 兰州大学 | 2021-08-24 | — | — | CN | claimed |
| EP-0736111-B1 | METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL | STORK SCREENS BV (NL) | 1999-04-21 | — | — | EP | claimed |
| EP-0736111-A1 | METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL | STORK SCREENS B.V. (NL) | 1996-10-09 | — | — | EP | claimed |
| WO-1995017534-A1 | METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL | STORK SCREENS B.V. (NL) | 1995-06-29 | — | — | WO | claimed |
| JP-55115270-A | — | — | None | — | — | JP | disclosed |
| CN-116457472-A | RNA aptamer sensor | 森斯艾普有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113288897-B | Application of neobynine derivatives in preparation of drugs for treating gastric cancer | 兰州大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-113321673-A | Preparation method and application of neobynine boric acid compound | 兰州大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-113288897-A | Application of neobynine derivatives in preparation of drugs for treating gastric cancer | 兰州大学 | 2021-08-24 | — | — | CN | disclosed |
| WO-2021110094-A1 | MITOCHONDRION/RIBONUCLEIC-ACID-TARGETING TRANSFERABLE PHOTOACTIVE PROBE AND USE THEREOF | 深圳先进技术研究院 | 2021-06-10 | — | — | WO | disclosed |
| EP-0985672-B1 | Method for purifying tetrakis(fluoroaryl)borate compounds | NIPPON CATALYTIC CHEM IND (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-5939172-A | Metallic screen material having a strand or fibre structure, and method for manufacturing such a material | STORK SCREENS B.V. (NL) | 1999-08-17 | — | — | US | disclosed |
| EP-0736111-B1 | METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL | STORK SCREENS BV (NL) | 1999-04-21 | — | — | EP | disclosed |
| CN-1033698-C | Process for production of carboxylic cid anhydrides | BP CHEM INT LTD (GB) | 1997-01-01 | — | — | CN | disclosed |
| EP-0736111-A1 | METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL | STORK SCREENS B.V. (NL) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017534-A1 | METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL | STORK SCREENS B.V. (NL) | 1995-06-29 | — | — | WO | disclosed |
| CN-1061401-A | The preparation method of carboxylic acid anhydride | BP CHEM INT LTD (GB) | 1992-05-27 | — | — | CN | disclosed |
| JP-S55115270-A | BATTERY | YUASA BATTERY CO LTD | 1980-09-05 | — | — | JP | disclosed |