Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106166 | 0.89 | ITGB1 (0.45) | ITGB1ITGA4 | |
| SCHEMBL7099758 | 0.84 | ITGB1 (0.48) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1818220 | 0.84 | ITGB1 (0.48) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1821054 | 0.83 | ITGB1 (0.39) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7106236 | 0.83 | ITGB1 (0.39) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1818339 | 0.83 | ITGB1 (0.38) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1818342 | 0.81 | L3MBTL1 (0.35) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7382602 | 0.81 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7100078 | 0.81 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL1821102 | 0.81 | ITGB1 (0.43) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183241-B1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6399643-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-04 | — | — | US | disclosed |
| EP-1183241-A1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | Aventis Pharma Deutschland GmbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069831-A1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-23 | — | — | WO | disclosed |