Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 20/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 19/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 19/20 | 0.54 |
| ▸ | F2 | P00734 | 16/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6161749 | 0.89 | F10 (0.47) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6161269 | 0.87 | F10 (0.71) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6203384 | 0.85 | F10 (0.76) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6164502 | 0.84 | TRPV1 (0.44) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6238659 | 0.83 | DHODH (0.39) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6166037 | 0.82 | F10 (0.74) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6166071 | 0.80 | F10 (0.66) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7494748 | 0.78 | F10 (0.73) | F10PRSS1PRSS2PRSS3F2 | |
| Fluoroacetate SCHEMBL6182231 | 0.76 | TRPV1 (0.41) | — | |
| Trifluoroacetic Acid SCHEMBL6161745 | 0.74 | PRSS1 (0.63) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | claimed |
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | F10 11/4885PRSS1 43/4885PRSS2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.