Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101427 | 0.87 | CYSLTR2 (0.51) | MAOBMAOAKCNH2KDM1ABCHE | |
| SCHEMBL23364576 | 0.86 | CYSLTR2 (0.53) | MAOBMAOAKCNH2KDM1ATNKS2 | |
| SCHEMBL23364801 | 0.82 | KCNH2 (0.49) | MAOBKCNH2KDM1ATNKS2BCHE | |
| SCHEMBL23380025 | 0.82 | KDM1A (0.48) | MAOBMAOAKCNH2KDM1ATNKS2 | |
| SCHEMBL29932805 | 0.82 | MAOB (0.50) | MAOBMAOAKCNH2KDM1ATNKS2 | |
| SCHEMBL7098576 | 0.82 | MAOB (0.50) | MAOBMAOAKCNH2KDM1ATNKS2 | |
| SCHEMBL23379988 | 0.81 | KCNH2 (0.47) | MAOBMAOAKCNH2KDM1ATNKS2 | |
| SCHEMBL6583019 | 0.80 | MAOB (0.56) | MAOBMAOAKCNH2KDM1ATNKS2 | |
| SCHEMBL23364632 | 0.79 | KDM1A (0.46) | MAOBKCNH2KDM1ATNKS2BCHE | |
| SCHEMBL29932780 | 0.77 | KDM1A (0.44) | MAOBKCNH2KDM1ATNKS2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |