Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101475 | 0.87 | MAOB (0.46) | CYSLTR2CYSLTR1MRGPRX4MAOBMAOA | |
| SCHEMBL7101436 | 0.81 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1MRGPRX4MAOBMAOA | |
| SCHEMBL10272647 | 0.78 | MRGPRX4 (0.64) | MRGPRX4MAOBMAOAKDM1ALIPG | |
| SCHEMBL6464841 | 0.77 | FDFT1 (0.42) | CYSLTR2CYSLTR1MRGPRX4MAOBMAOA | |
| SCHEMBL6464838 | 0.77 | FDFT1 (0.42) | CYSLTR2CYSLTR1MRGPRX4MAOBMAOA | |
| SCHEMBL15635448 | 0.77 | MRGPRX4 (0.56) | MRGPRX4MAOBMAOAKDM1ALIPG | |
| SCHEMBL6457722 | 0.75 | FDFT1 (0.41) | CYSLTR2CYSLTR1MRGPRX4MAOBMAOA | |
| SCHEMBL6457727 | 0.75 | FDFT1 (0.41) | CYSLTR2CYSLTR1MRGPRX4MAOBMAOA | |
| SCHEMBL27984510 | 0.74 | AKR1C3 (0.39) | MAOBMAOAKDM1ATP53 | |
| SCHEMBL8999827 | 0.74 | MRGPRX4 (0.54) | MRGPRX4MAOBMAOAKDM1ALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |