Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 4/20 | 0.40 |
| ▸ | ATP4B | P51164 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283547 | 0.85 | NUDT1 (0.57) | NUDT1TLR8 | |
| SCHEMBL18072508 | 0.82 | NUDT1 (0.61) | NUDT1TLR8PIM1HRH3LMNA | |
| SCHEMBL30590643 | 0.81 | HRH3 (0.56) | NUDT1HTR1BPIM1HRH3PIM3 | |
| SCHEMBL18072382 | 0.76 | NUDT1 (0.57) | NUDT1TLR8PIM1HRH3 | |
| SCHEMBL11036646 | 0.75 | NUDT1 (0.65) | NUDT1TLR8PIM1HRH3LMNA | |
| SCHEMBL18072383 | 0.74 | NUDT1 (0.55) | NUDT1TLR8PIM1HRH3 | |
| SCHEMBL31201109 | 0.74 | NUDT1 (0.59) | NUDT1HRH3 | |
| SCHEMBL31403790 | 0.72 | NUDT1 (0.57) | NUDT1PIM1HRH3 | |
| SCHEMBL31201204 | 0.70 | NUDT1 (0.63) | NUDT1TLR8HRH3 | |
| SCHEMBL28189689 | 0.69 | NUDT1 (0.61) | NUDT1TLR8HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751170-B1 | Silicone derivatives, their production and use | CHIBA FLOUR MILLING (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5859243-A | AMINOSILICONES HAVING PYRIMIDINYL GROUPS BOUND TO THE AMINO GROUPS; USED TO GEL SILICONE OIL OR TO INCREASE THE VISCOSITY STABLY AND HOMOGENEOUSLY; BASES FOR COSMETICS, DRUGS, INDUSTRIAL MATERIAL; FEEL; TEXTURE | CHIBA FLOUR MILLING CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5712391-A | POLYSILOXANES MODIFIED WITH TRIAZINE GROUPS AND DIAMINE COMPOUNDS FOR COSMETICS | CHIBA FLOUR MILLING CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0751170-A2 | Silicone derivatives, their production and use | Chiba Flour Milling Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |