Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334056 | 0.87 | HTT (0.72) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL12426042 | 0.85 | HTT (0.82) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL10802959 | 0.85 | HTT (0.68) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL1496463 | 0.84 | HTT (0.67) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL13043458 | 0.83 | HTT (0.65) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL5881710 | 0.82 | HTT (0.64) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL13043696 | 0.82 | HTT (0.64) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL20797630 | 0.80 | HTT (0.61) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL7972064 | 0.80 | HTT (0.61) | HTTMAPTTDP1ALDH3A1POLB | |
| SCHEMBL27516048 | 0.79 | HTT (0.72) | HTTMAPTTDP1ALDH3A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099242-A1 | COSMETIC AGENTS CONTAINING PROTEIN DISULFIDE ISOMERASE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-12-04 | — | — | WO | disclosed |