Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043696 | 0.93 | HTT (0.64) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL10802959 | 0.86 | HTT (0.68) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL13043458 | 0.81 | HTT (0.65) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL2334056 | 0.81 | HTT (0.72) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL7970378 | 0.80 | TDP1 (0.46) | SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL7101559 | 0.80 | HTT (0.70) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL7970570 | 0.80 | KAT2B (0.71) | SMN1; SMN2ALDH1A1NPSR1MAPTTDP1 | |
| SCHEMBL17208819 | 0.80 | SMN1; SMN2 (0.69) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL7973678 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1NPSR1MAPTTDP1 | |
| SCHEMBL12426042 | 0.79 | HTT (0.82) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |