Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448316 | 1.00 | DPP4 (0.31) | DPP4 | |
| SCHEMBL4448472 | 0.94 | — | — | |
| SCHEMBL7102347 | 0.94 | — | — | |
| SCHEMBL4449150 | 0.91 | HCRTR1 (0.32) | DPP4 | |
| SCHEMBL7101164 | 0.91 | HCRTR1 (0.32) | DPP4 | |
| SCHEMBL5092214 | 0.85 | — | — | |
| SCHEMBL6803954 | 0.85 | CHRM2 (0.30) | — | |
| SCHEMBL6803078 | 0.84 | GAA (0.34) | DPP4 | |
| SCHEMBL6803730 | 0.84 | NPC1 (0.33) | DPP4 | |
| SCHEMBL7100766 | 0.84 | F2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362052-A1 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | Amura Therapeutics Limited (GB) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002057270-A1 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | AMURA THERAPEUTICS LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |