Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627282 | 0.78 | IDO1 (0.38) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL7099703 | 0.78 | IDO1 (0.38) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL5998737 | 0.75 | MAPT (0.62) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL1624772 | 0.75 | KDM4E (0.48) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL3636537 | 0.73 | TAAR1 (0.61) | ALDH1A1KDM4ETAAR1MAOBCNR1 | |
| SCHEMBL15638573 | 0.72 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL11390047 | 0.71 | ALDH1A1 (0.81) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL11397234 | 0.69 | MAPT (0.71) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL29824523 | 0.67 | MAPT (0.68) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL15875869 | 0.67 | MAPT (0.68) | ALDH1A1GAAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |