Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.67 |
| ▸ | CD74 | P04233 | 9/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980660 | 0.86 | CTSS (0.66) | CTSSCD74 | |
| SCHEMBL14096747 | 0.85 | CTSS (0.64) | CTSSCD74 | |
| SCHEMBL2975020 | 0.84 | CTSS (0.64) | CTSSCD74 | |
| SCHEMBL2967059 | 0.84 | CTSS (0.71) | CTSSCD74 | |
| SCHEMBL2978007 | 0.84 | CTSS (0.63) | CTSSCD74 | |
| SCHEMBL2985107 | 0.83 | CTSS (0.62) | CTSSCD74 | |
| SCHEMBL2973696 | 0.83 | CTSS (0.62) | CTSSCD74 | |
| SCHEMBL13222336 | 0.83 | CTSS (0.69) | CTSSCD74 | |
| SCHEMBL2982525 | 0.82 | CTSS (0.68) | CTSSCD74 | |
| SCHEMBL2975010 | 0.82 | CTSS (0.61) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309591-A2 | SUBSTITUTED PYRAZOLES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-05-14 | — | — | EP | claimed |
| WO-2002014314-A2 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2002-02-21 | — | — | WO | claimed |