SCHEMBL7101864

SCHEMBL7101864

C=CC(=O)OCCCO[Si](OC(=C)C)(OC(=C)C)OC(=C)C

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 1/20 0.51
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9228399 0.89 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5835079 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8963456 0.80 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28105549 0.80 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3293446 0.79 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27329592 0.79 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8900217 0.79 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7101860 0.79 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.76 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27379810 0.76 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1038934-B1 Base coat composition KANSAI PAINT CO LTD (JP) 2003-09-03 EP disclosed
EP-0768350-B1 Base coat composition for forming topcoat and coating method using same KANSAI PAINT CO LTD (JP) 2002-03-13 EP disclosed
EP-1038934-A2 Base coat composition KANSAI PAINT CO., LTD. (JP) 2000-09-27 EP disclosed
US-5902644-A LAMINATING THE UNDERCOATINGS COMPRISING AT LEAST ONE OF EPOXY-CONTAINING COMPOUND AND CARBOXY-CONTAINING COMPOUND HAVING A HYDROXY GROUP, FORMING A PROTECTIVE COATINGS HAVING ACID RESISTANCE, CHIPPING RESISTANCE, RECOAT ADHESION KANSAI PAINT COMPANY, LIMITED (JP) 1999-05-11 US disclosed
US-5898052-A BASE COAT COMPRISING COMPOUND HAVING TWO EPOXY GROUPS IN ONE MOLECULE, COMPOUND HAVING TWO CARBOXYL GROUPS IN ONE MOLECULE, AT LEAST ONE COMPONENT ALSO HAVING HYDROXYL GROUP, MELAMINE RESIN, PIGMENT KANSAI PAINT COMPANY, LTD. (JP) 1999-04-27 US disclosed
EP-0768350-A2 Base coat composition for forming topcoat and coating method using same KANSAI PAINT CO., LTD. (JP) 1997-04-16 EP disclosed