Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102408 | 1.00 | ADORA2A (0.71) | ADORA2AADORA3ADORA2BADORA1 | |
| Formic Acid SCHEMBL7102289 | 0.96 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 | |
| Formic Acid SCHEMBL7102280 | 0.96 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7102281 | 0.90 | ADORA2A (0.61) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7102282 | 0.90 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7102294 | 0.83 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7117701 | 0.82 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8609271 | 0.82 | ADORA2A (1.00) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7117696 | 0.82 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8609268 | 0.82 | ADORA2A (1.00) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090021-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | claimed |
| US-6534486-B1 | With broad anti-inflammatory properties which inhibit leukocyte recruitment and activation and which are agonists of the adenosine 2a receptor are described. | SMITHKLINE BEECHAM CORPORATION | 2003-03-18 | — | — | US | claimed |
| EP-1090021-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067266-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | claimed |