Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678883 | 0.89 | HDAC2 (0.74) | HDAC2KMT2APOLBLTA4HMEN1 | |
| SCHEMBL16964230 | 0.83 | HDAC2 (0.57) | HDAC2KMT2AMETAP2POLBL3MBTL1 | |
| SCHEMBL4747179 | 0.83 | POLB (0.50) | HDAC2KMT2AMETAP2POLBL3MBTL1 | |
| SCHEMBL2735379 | 0.81 | HDAC2 (0.59) | HDAC2KMT2AMETAP2POLBGAA | |
| SCHEMBL4888030 | 0.79 | ROCK1 (0.54) | HDAC2KMT2AMETAP2POLBL3MBTL1 | |
| SCHEMBL28548192 | 0.77 | POLB (0.55) | HDAC2KMT2AMETAP2POLBGAA | |
| SCHEMBL4594451 | 0.75 | MEN1 (0.62) | HDAC2KMT2AMETAP2POLBGAA | |
| SCHEMBL28022968 | 0.75 | POLB (0.53) | HDAC2KMT2AMETAP2POLBGAA | |
| SCHEMBL3242251 | 0.75 | HDAC2 (0.97) | HDAC2LTA4H | |
| SCHEMBL2788251 | 0.75 | KMT2A (0.50) | HDAC2KMT2AMETAP2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278912-A2 | HYDROXY-PHENOXYETHER POLYMERS IN PAPERMAKING | Advanced Plastics Technologies, Ltd (GB) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001046523-A2 | HYDROXY-PHENOXYETHER POLYMERS IN PAPERMAKING | ADVANCED PLASTICS TECHNOLOGIES, LTD. (GB) | 2001-06-28 | — | — | WO | disclosed |