SCHEMBL7102524

SCHEMBL7102524

CCCCCCCCCCC(O)C(S)CC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 2/20 0.54
CYP2D6 P10635 2/20 0.50
LMNA P02545 2/20 0.50
GMNN O75496 1/20 0.50
POLB P06746 1/20 0.50
THPO P40225 1/20 0.50
MTOR P42345 1/20 0.50
BLM P54132 1/20 0.50
KDM4E B2RXH2 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
CETP P11597 1/20 0.50
HTT P42858 1/20 0.50
UBE2N P61088 1/20 0.50
GPR84 Q9NQS5 7/20 0.43
FFAR1 O14842 1/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653789 0.86 SPHK1 (0.52) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL11242803 0.80
SCHEMBL11799259 0.80 LMNA (0.48) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22804812 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22805015 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22804794 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22805047 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22805001 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22804810 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL22804708 0.80 SPHK1 (0.68) SPHK1CYP2D6LMNAGMNNPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1346014-A2 FRICTION MODIFIERS FOR ENGINE OIL COMPOSITION Infineum International Ltd. (GB) 2003-09-24 EP claimed
WO-2002061020-A2 FRICTION MODIFIERS FOR ENGINE OIL COMPOSITION INFINEUM INTERNATIONAL LIMITED (US) 2002-08-08 WO claimed
US-6358896-B1 LUBRICANT MIXTUE OF KETO-AMIDE FROMED FROM ALKYL ACETOACETATE WITH FATTY AMINE; AND KETO-ESTER FORMED BY ESTER INTERCHANGE OF ALKYL ACETOACETATE AND FATTY ALCOHOL, HYDROXYALKYL SULFIDE, OR ETHOXYLATED FATTY AMINE INFINEUM INTERNATIONAL LTD. (GB) 2002-03-19 US claimed