⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102670 | 1.00 | — | — | |
| SCHEMBL765228 | 0.89 | PTGS1 (0.33) | — | |
| SCHEMBL10195944 | 0.89 | PTGS1 (0.33) | — | |
| SCHEMBL10476740 | 0.89 | PTGS1 (0.33) | — | |
| SCHEMBL3437283 | 0.89 | PTGS1 (0.33) | — | |
| SCHEMBL19416688 | 0.89 | PTGS1 (0.33) | — | |
| SCHEMBL18643686 | 0.78 | — | — | |
| SCHEMBL18660027 | 0.78 | — | — | |
| SCHEMBL8232714 | 0.75 | — | — | |
| SCHEMBL24616618 | 0.74 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994882-B1 | MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS | DU PONT (US) | 2003-09-10 | — | — | EP | claimed |
| US-6207847-B1 | REACTING AN EPOXIDE WITH AN AZIDOTRIMETHYLSILANE; THEN HYDROCARBON HALIDE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-03-27 | — | — | US | claimed |
| EP-0994882-B1 | MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS | DU PONT (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6207847-B1 | REACTING AN EPOXIDE WITH AN AZIDOTRIMETHYLSILANE; THEN HYDROCARBON HALIDE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-03-27 | — | — | US | disclosed |
| EP-0994882-A1 | MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999002535-A1 | MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |