SCHEMBL24616618

SCHEMBL24616618

COCC1CC2CCC(C1)O2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18660027 0.90
SCHEMBL24615868 0.78
SCHEMBL23666349 0.75 MEN1 (0.32)
SCHEMBL18643686 0.74
SCHEMBL10271206 0.74 PIK3CD (0.33) PIK3CD
SCHEMBL7102668 0.74
SCHEMBL7102670 0.74
SCHEMBL13564251 0.73 MEN1 (0.34)
SCHEMBL10107071 0.72 JAK2 (0.31)
SCHEMBL17253449 0.72 JAK2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148422-A1 BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF BEIGENE, LTD. (KY) 2022-07-14 WO disclosed