Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101194 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1MAPK1KMT2AAR | |
| SCHEMBL4609823 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1MAPK1KMT2AAR | |
| SCHEMBL5362613 | 0.80 | CA1 (0.39) | SMN1; SMN2ARHSD17B10CA12CA1 | |
| SCHEMBL29449219 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2MEN1MAPK1KMT2ATSHR | |
| SCHEMBL40549 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2MEN1MAPK1KMT2ATSHR | |
| SCHEMBL11371728 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1MAPK1KMT2AAR | |
| SCHEMBL13974786 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1MAPK1KMT2AAR | |
| SCHEMBL1820232 | 0.78 | MAPT (0.42) | SMN1; SMN2MEN1MAPK1KMT2AAR | |
| Hydrochloric Acid SCHEMBL11772004 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2MEN1MAPK1KMT2ATSHR | |
| SCHEMBL11245521 | 0.77 | AR (0.46) | SMN1; SMN2MEN1MAPK1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |