Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779761 | 0.83 | ACP3 (0.44) | ACP3AOC3MEN1KMT2APNMT | |
| SCHEMBL8130729 | 0.83 | ACP3 (0.44) | ACP3AOC3MEN1KMT2APNMT | |
| SCHEMBL7786059 | 0.83 | ACP3 (0.44) | ACP3AOC3MEN1KMT2APNMT | |
| SCHEMBL954860 | 0.82 | AOC3 (0.42) | ACP3AOC3MEN1KMT2APNMT | |
| SCHEMBL31173890 | 0.79 | ACP3 (0.41) | ACP3AOC3MEN1KMT2APNMT | |
| SCHEMBL7107297 | 0.79 | ADRB3 (0.48) | ACP3MEN1KMT2ATSHRRECQL | |
| SCHEMBL7105071 | 0.79 | ADRB3 (0.48) | ACP3MEN1KMT2ATSHRRECQL | |
| SCHEMBL16953337 | 0.79 | ACP3 (0.41) | ACP3AOC3MEN1KMT2APNMT | |
| SCHEMBL8098427 | 0.79 | ADRB3 (0.48) | ACP3MEN1KMT2ATSHRRECQL | |
| SCHEMBL17061793 | 0.78 | ACP3 (0.46) | ACP3AOC3MEN1KMT2APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9249600-A | — | — | None | — | — | JP | disclosed |
| JP-9030998-A | — | — | None | — | — | JP | disclosed |
| JP-11343253-A | — | — | None | — | — | JP | disclosed |
| CN-103596951-A | 8-ethyl-6-(aryl)pyrido [2,3-d]pyrimidin-7(8h)-ones for the treatment of nervous system disorders and cancer | AFRAXIS INC | 2014-02-19 | — | — | CN | disclosed |
| CN-101808992-B | 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives | HOFFMANN LA ROCHE | 2012-09-26 | — | — | CN | disclosed |
| CN-102648200-A | 8-ethyl-6-(aryl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders | AFRAXIS INC | 2012-08-22 | — | — | CN | disclosed |
| CN-102348682-A | 1,1,1-trifluoro-2-hydroxypropyl compounds | HOFFMANN LA ROCHE | 2012-02-08 | — | — | CN | disclosed |
| CN-101538268-B | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER | 2011-07-27 | — | — | CN | disclosed |
| CN-101432262-B | Cyclohexyl-substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 | LILLY CO ELI | 2011-06-01 | — | — | CN | disclosed |
| CN-101808992-A | 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives | HOFFMANN LA ROCHE | 2010-08-18 | — | — | CN | disclosed |
| CN-1289321-A | Biphenylsulfonyl cyanamides, method for the production thereof and their utilization as a medicament | AVENTIS PHARMACEUTIC DEUTSCHLA (DE) | 2001-03-28 | — | — | CN | disclosed |
| EP-0754665-B1 | 3-substituted-alpha,beta-dibromoethylbenzene and process for preparing the same | MITSUBISHI CHEM CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| JP-H11343253-A | PRODUCTION OF ALPHA, BETA-DIBROMOETHYLBENZENE AND ALPHA-BROMOSTYRENE | MITSUBISHI CHEMICAL CORP | 1999-12-14 | — | — | JP | disclosed |
| US-5841004-A | 3-substituted-α, β-dibromoethylbenzene and process for preparing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5841001-A | ALLOWING 2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL TO CONTACT ENZYME STEREOSELECTIVELY CATALYZING ESTER INTERCHANGE IN PRESENCE OF CARBOXYLIC ANHYDRIDE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| CN-1188760-A | Benzidine-sulfuryl radical substitution pentatomic heterocycle, its preparation method, its medicinal and composition | HOECHST AG (DE) | 1998-07-29 | — | — | CN | disclosed |
| JP-H09249600-A | PRODUCTION OF 2-BROMO-1-(M-SUBSTITUTED PHENYL)ETHANOLS | MITSUBISHI CHEM CORP | 1997-09-22 | — | — | JP | disclosed |
| EP-0792936-A2 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | Mitsubishi Chemical Corporation (JP) | 1997-09-03 | — | — | EP | disclosed |
| JP-H0930998-A | PRODUCTION OF M-SUBSTITUTED-ALPHA-HYDROXYMETHYLSTYRENE DERIVATIVE AND 3-CHLORO-ALPHA-BROMOSTYRENE | MITSUBISHI CHEM CORP | 1997-02-04 | — | — | JP | disclosed |
| EP-0754665-A2 | 3-substituted-alpha,beta-dibromoethylbenzene and process for preparing the same | Mitsubishi Chemical Corporation (JP) | 1997-01-22 | — | — | EP | disclosed |