SCHEMBL7102928

SCHEMBL7102928

COCCc1nc2c(N)nc3c(c2n1CCOCCNC(=O)N(C)c1ccccc1)CCCC3

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483634 0.88 TLR7 (0.44) TLR7
SCHEMBL31006028 0.88 TLR7 (0.44) TLR7
SCHEMBL4343043 0.86 TLR7 (0.40) TLR7
SCHEMBL7089752 0.85 TLR7 (0.55) TLR7
SCHEMBL7101492 0.84 TLR7 (0.44) TLR7
SCHEMBL4336076 0.83 TLR7 (0.43) TLR7
SCHEMBL6031144 0.82 TLR7 (0.44) TLR7
SCHEMBL3865322 0.81 TLR7 (0.48) TLR7
SCHEMBL5748740 0.81 TLR7 (0.42) TLR7
SCHEMBL5750020 0.80 TLR7 (0.48) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1343784-A2 UREA SUBSTITUTED IMIDAZOQUINOLINE ETHERS 3M Innovative Properties Company (US) 2003-09-17 EP disclosed
WO-2002046191-A2 UREA SUBSTITUTED IMIDAZOQUINOLINE ETHERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-06-13 WO disclosed