Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099889 | 1.00 | OPRK1 (0.48) | OPRK1HRH1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7099786 | 1.00 | OPRK1 (0.48) | OPRK1HRH1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7097077 | 1.00 | OPRK1 (0.48) | OPRK1HRH1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7096727 | 0.94 | OPRK1 (0.46) | OPRK1HRH1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7102820 | 0.89 | OPRK1 (0.60) | OPRK1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL299718 | 0.89 | OPRK1 (0.60) | OPRK1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL7099886 | 0.89 | OPRK1 (0.60) | OPRK1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL7102877 | 0.88 | OPRK1 (0.59) | OPRK1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL295478 | 0.86 | KMT2A (0.59) | OPRK1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL7101189 | 0.86 | KMT2A (0.59) | OPRK1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782992-B1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6335444-B1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-01 | — | — | US | disclosed |
| US-5907039-A | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0782992-A1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) | 1997-07-09 | — | — | EP | disclosed |