⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030303 | 0.78 | — | — | |
| SCHEMBL1163352 | 0.73 | — | — | |
| SCHEMBL10669462 | 0.73 | — | — | |
| SCHEMBL569712 | 0.73 | — | — | |
| SCHEMBL1749965 | 0.72 | — | — | |
| SCHEMBL5474767 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6177026 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL2775602 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL11853604 | 0.71 | — | — | |
| SCHEMBL2286014 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137606-A1 | METHODS AND MODIFICATIONS THAT PRODUCE ssRNAi COMPOUNDS WITH ENHANCED ACTIVITY, POTENCY AND DURATION OF EFFECT | Smith, Larry J. (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015168661-A1 | METHODS AND MODIFICATIONS THAT PRODUCE ssRNAi COMPOUNDS WITH ENHANCED ACTIVITY, POTENCY AND DURATION OF EFFECT | SMITH LARRY J (US) | 2015-11-05 | — | — | WO | disclosed |
| EP-0988551-B1 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | BAYER AG (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6287568-B1 | FORMING ANTIBODIES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2001-09-11 | — | — | US | disclosed |
| US-6165800-A | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays | BAYER CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-6071505-A | APPLYING HAIR CONDITIONER HAVING A DIQUATERNARY AMMONIUM CARBOXYMETHYL CELLULOSE DERIVATIVE BACTERICIDE | BOARD OF SUPERVISORS OF LOUISANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0988551-A2 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | Bayer Corporation (US) | 2000-03-29 | — | — | EP | disclosed |
| US-5981737-A | CARBOXYMETHYL CELLULOSE DERIVATIVE WITH SOME OR ALL OF CARBOXYMETHYL GROUPS REPLACED BY DIQUATERNARY AMMONIUM GROUPS; FOR HAIR CONDITIONERS, ANTISTATIC AGENTS, BACTERICIDES, FLOCCULANTS, DRUG BINDING/DRUG DELIVERY AGENTS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1999-11-09 | — | — | US | disclosed |
| WO-1999012416-A1 | T-INDEPENDENT CONJUGATE-VACCINES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-03-18 | — | — | WO | disclosed |
| WO-1998054574-A2 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | BAYER CORPORATION (US) | 1998-12-03 | — | — | WO | disclosed |
| US-5633232-A | ANALGESIC, ANTIHISTAMINE, SKIN DISORDERS, VISION DEFECTS,ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5468731-A | Peptide compounds, a process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5420297-A | Antiinflammatory agents, ophthalmic and antiarthritic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| WO-1994020126-A1 | USE OF PEPTIDES FOR THE MANUFACTURE OF A MEDICAMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |
| EP-0590152-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0443132-B1 | Peptides having tachykinin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992022569-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | WO | disclosed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |