Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7103017

N.N.c1cn(CCCCn2ccnc2)cn1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 9/20 0.90
PRKCI P41743 1/20 0.57
HMOX1 P09601 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937596 0.97 TBXAS1 (0.95) TBXAS1PRKCIHMOX1
SCHEMBL2535103 0.95 TBXAS1 (1.00) TBXAS1
SCHEMBL2532389 0.95 TBXAS1 (1.00) TBXAS1
Hydrochloric Acid SCHEMBL1775618 0.95 TBXAS1 (0.90) TBXAS1PRKCIHMOX1
SCHEMBL2533366 0.95 TBXAS1 (1.00) TBXAS1
SCHEMBL10247600 0.95 TBXAS1 (1.00) TBXAS1
SCHEMBL939851 0.95 TBXAS1 (1.00) TBXAS1
SCHEMBL937530 0.95 TBXAS1 (1.00) TBXAS1
SCHEMBL1679410 0.95 TBXAS1 (1.00) TBXAS1
SCHEMBL285054 0.95 TBXAS1 (1.00) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051144-B1 USE OF HETEROCYCLIC QUATERNARY POLYAMMONIUM POLYMERS AS PROTECTIVE AGENT FOR KERATIN FIBRES AND COSMETIC COMPOSITIONS OREAL (FR) 2003-09-03 EP disclosed
US-6416770-B1 Use of heterocyclic quaternary polyammonium polymers as protective agent for keratin fibres and cosmetic compositions L'ORéAL S.A. (FR) 2002-07-09 US disclosed
US-6240929-B1 POLYSILOXANES WITH HETEROCYCLIC QUATERNARY AMMONIUM GROUPS FOR DETANGLING HAIR AND KERATIN FIBERS L'OREAL S.A. (FR) 2001-06-05 US disclosed
EP-1051144-A1 USE OF HETEROCYCLIC QUATERNARY POLYAMMONIUM POLYMERS AS PROTECTIVE AGENT FOR KERATIN FIBRES AND COSMETIC COMPOSITIONS L'OREAL (FR) 2000-11-15 EP disclosed
WO-1999037276-A1 USE OF HETEROCYCLIC QUATERNARY POLYAMMONIUM POLYMERS AS PROTECTIVE AGENT FOR KERATIN FIBRES AND COSMETIC COMPOSITIONS L'OREAL (FR) 1999-07-29 WO disclosed