Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.69 |
| ▸ | CNR2 | P34972 | 2/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.69 |
| ▸ | TUBB | P07437 | 2/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.69 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.69 |
| ▸ | ESR1 | P03372 | 9/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026252 | 0.94 | CNR1 (0.78) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL31683596 | 0.93 | TUBB4A (0.60) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL11551310 | 0.92 | ESR1 (0.65) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL11552625 | 0.89 | CNR2 (0.88) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7075354 | 0.89 | CNR1 (0.70) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7148725 | 0.89 | CNR1 (0.70) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL1665792 | 0.89 | CNR1 (0.70) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL6836439 | 0.88 | CNR1 (0.69) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL22190469 | 0.88 | CNR1 (0.69) | CNR1CNR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7098723 | 0.88 | CNR1 (0.69) | CNR1CNR2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838464-B1 | Substituted benzo(b)thiophene compounds having activity as selective estrogen receptor modulators | LILLY CO ELI (US) | 2003-09-10 | — | — | EP | claimed |
| EP-0838464-A1 | Substituted benzo(b)thiophene compounds having activity as selective estrogen receptor modulators | ELI LILLY AND COMPANY (US) | 1998-04-29 | — | — | EP | claimed |
| US-5962475-A | OSTEOPOROSIS, RESTENOSIS, BREAST CANCER | ELI LILLY AND COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| US-5827876-A | MODIFYING BALANCE BETWEEN BONE RESORPTION AND PRODUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-27 | — | — | US | disclosed |