Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103143 | 1.00 | GSK3B (0.35) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL5089143 | 0.82 | GSK3B (0.52) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL5024316 | 0.74 | GSK3B (0.54) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL5089226 | 0.71 | GSK3B (0.60) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL5023309 | 0.69 | GSK3B (0.49) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL7853388 | 0.69 | GSK3B (0.49) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL14096867 | 0.68 | GSK3B (0.47) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL7856003 | 0.68 | KMT2A (0.44) | — | |
| SCHEMBL7853495 | 0.67 | GSK3B (0.46) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL7023251 | 0.67 | GSK3B (0.46) | GSK3BCCNB2CDK1CCNB1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |