Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 3/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16785311 | 0.85 | — | — | |
| SCHEMBL17520183 | 0.82 | SLC6A3 (0.44) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL26940470 | 0.81 | EPHX1 (0.37) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL9029529 | 0.81 | EPHX1 (0.37) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL27388979 | 0.79 | CPN1 (0.47) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL24328846 | 0.79 | EPHX1 (0.40) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL1050730 | 0.79 | EPHX1 (0.40) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL1050728 | 0.79 | EPHX1 (0.40) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL8770267 | 0.78 | SLC6A2 (0.46) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7752468 | 0.78 | CPN1 (0.46) | CPN1CPB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224186-B1 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | MILLENNIUM PHARM INC (US) | 2003-09-24 | — | — | EP | disclosed |