Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105625 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL6699766 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL6107128 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL15924842 | 0.74 | LMNA (0.46) | SMN1; SMN2LMNAMAPK1KMT2APOLB | |
| SCHEMBL6696791 | 0.73 | AGXT (0.40) | SMN1; SMN2LMNAKMT2APOLBMEN1 | |
| SCHEMBL6700111 | 0.73 | MAPK1 (0.40) | SMN1; SMN2LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL1893306 | 0.73 | KMT2A (0.47) | SMN1; SMN2LMNAMAPK1KMT2AALDH1A1 | |
| Water SCHEMBL29438456 | 0.73 | DPP4 (0.45) | SMN1; SMN2LMNAKMT2AALDH1A1POLB | |
| Water SCHEMBL22718534 | 0.73 | DPP4 (0.45) | SMN1; SMN2LMNAKMT2AALDH1A1POLB | |
| SCHEMBL6108037 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341789-A2 | ARYL ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002046189-A2 | ARYL ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |