Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93318 | 0.84 | MEN1 (0.37) | MEN1KMT2ARAB9AMTNR1AMTNR1B | |
| SCHEMBL8841068 | 0.84 | ELANE (0.44) | THRBSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL471917 | 0.84 | MEN1 (0.37) | MEN1KMT2ARAB9AMTNR1AMTNR1B | |
| SCHEMBL28759729 | 0.81 | CYP1A2 (0.37) | SMN1; SMN2MEN1KMT2ACYP2C19GAA | |
| SCHEMBL28413078 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EMEN1KMT2AGAA | |
| SCHEMBL29443449 | 0.77 | EP300 (0.41) | — | |
| SCHEMBL3468377 | 0.76 | MEN1 (0.39) | SMN1; SMN2KDM4EMEN1KMT2AGAA | |
| SCHEMBL8968101 | 0.76 | — | — | |
| SCHEMBL29136592 | 0.76 | AKR1C3 (0.56) | SMN1; SMN2MEN1KMT2AGLAGAA | |
| SCHEMBL6993257 | 0.75 | ALDH1A1 (0.54) | MEN1KMT2AHTTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713583-B2 | INTRAOCULAR LENSES, INCLUDE CROSS- LINKED POLYMERIC MATERIALS HAVING A FIRST CONSTITUENT DERIVED FROM MONOMERIC ACRYLATES, METHACRYLATES AND SECOND CONSTITUENT AS A CROSS-LINKED POLYMERIC MATERIAL HAVING BRANCHED CHAIN ALKYL GROUP | ADVANCED MEDICAL OPTICS, INC. | 2004-03-30 | — | — | US | claimed |
| EP-1137956-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | Allergan Sales, Inc. (US) | 2001-10-04 | — | — | EP | claimed |
| US-20010005743-A1 | Intraocular lenses made from polymeric compositions | ALLERGAN SALES, INC. (US) | 2001-06-28 | — | — | US | claimed |
| US-6241766-B1 | Intraocular lenses made from polymeric compositions | ALLERGAN SALES, INC. | 2001-06-05 | — | — | US | claimed |
| WO-2000026698-B1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | ALLERGAN SALES INC (US) | 2000-07-13 | — | — | WO | claimed |
| WO-2000026698-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | ALLERGAN SALES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-106537632-B | Packaging structure body of OLED display introducing anti-reflection performance | 巴斯夫涂料有限公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-0860455-A2 | Photocrosslinkable polymers | Rolic AG (CH) | 1998-08-26 | — | — | EP | disclosed |