⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796446 | 0.85 | — | — | |
| SCHEMBL27775424 | 0.85 | — | — | |
| SCHEMBL329842 | 0.85 | — | — | |
| SCHEMBL21378 | 0.80 | ALDH1A1 (0.72) | — | |
| SCHEMBL580581 | 0.80 | ALDH1A1 (0.72) | — | |
| SCHEMBL174369 | 0.80 | ALDH1A1 (0.72) | — | |
| SCHEMBL19444447 | 0.80 | ALDH1A1 (0.72) | — | |
| SCHEMBL9642004 | 0.80 | ALDH1A1 (0.72) | — | |
| SCHEMBL247292 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL27774077 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165540-B1 | TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME (GB) | 2003-08-13 | — | — | EP | claimed |
| US-20250326743-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| WO-2025217212-A1 | MAC1 INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-16 | — | — | WO | disclosed |
| US-20250281424-A1 | SMALL MOLECULE ANTAGONISTS OF PF4 | ZHOU YUHANG (US) | 2025-09-11 | — | — | US | disclosed |
| EP-4527837-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-03-26 | — | — | EP | disclosed |
| CN-119638680-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119638681-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119638682-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119053591-A | Crystal form of triazinedione derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-116323598-B | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2004058709-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058736-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| EP-1436291-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | Aventis Pharma S.A. (FR) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003024967-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2003-03-27 | — | — | WO | disclosed |
| US-5919811-A | NEURODEGENERATIVE DISORDERS | GLAXO WELLCOME S.P.A. (IT) | 1999-07-06 | — | — | US | disclosed |
| EP-0813524-A1 | INDOLE DERIVATIVES AS EAA ANTAGONISTS | GLAXO WELLCOME S.p.A. (IT) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027588-A1 | INDOLE DERIVATIVES AS EAA ANTAGONISTS | GLAXO WELLCOME S.P.A. (IT) | 1996-09-12 | — | — | WO | disclosed |
| US-4125724-A | OF AN ISOCYANATE TO A FORMAMIDO, PLATINUM OR PALLADIUM CATALYST | BRISTOL-MYERS COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4000298-A | Novel fungicidal composition and method using benzimidazole derivatives | ROUSSEL-UCLAF (FR) | 1976-12-28 | — | — | US | disclosed |
| US-3932447-A | FUNGICIDES | ROUSSEL-UCLAF (FR) | 1976-01-13 | — | — | US | disclosed |