Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878698 | 0.88 | KMT2A (0.65) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL5557575 | 0.85 | KMT2A (0.73) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL608622 | 0.84 | KMT2A (0.71) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL17664987 | 0.84 | KMT2A (0.53) | KMT2AEPHX2CASP3 | |
| SCHEMBL3757636 | 0.82 | KMT2A (0.72) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL29792075 | 0.82 | KMT2A (0.90) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL178801 | 0.82 | KMT2A (0.90) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL29370234 | 0.82 | KMT2A (0.90) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL7113144 | 0.81 | KMT2A (0.75) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL1853371 | 0.81 | KMT2A (0.64) | KMT2AEPHX2CASP3FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649613-B1 | Integrin inhibitors | MERCK PATENT GMBH (DE) | 2003-11-18 | — | — | US | disclosed |
| EP-1194401-B1 | DIACYLHYDRAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-1194401-A1 | DIACYLHYDRAZINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001005753-A1 | DIACYLHYDRAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-01-25 | — | — | WO | disclosed |